Nevus lipomatosus cutaneus superficialis (Hoffmann-Zurhelle) in a chimpanzee (Pan troglodytes).
نویسندگان
چکیده
BACKGROUND A 32-year-old, male chimpanzee (Pan troglodytes) kept in a zoo developed a focally extensive, proliferative, cerebriform, dermal mass at the left inner thigh extending to the inguinal region. After surgical removal, the mass recurred and extended progressively over a period of 5 years. METHODS AND RESULTS At necropsy, a 20 x 20 cm large, well defined, papular and partly verrucous, rubbery mass composed of multiple large, soft nodules measuring up to 4 cm in diameter was observed in the left thigh and inguinal region. Histological examination revealed a multifocal expansion of the dermis by mature adipocytes that were arranged in small islands to large lobular aggregates. Dermal proliferations of adipocytes were almost completely separated from the subcutaneous adipose tissue. CONCLUSIONS This is the first report of a unique lesion that resembles human Nevus lipomatosus cutaneus superficialis in a chimpanzee and is different from lipoma or liposarcoma.
منابع مشابه
Nevus lipomatosus cutaneous superficialis.
Two cases of naevus lipomatosus superficialis (Hoffmann and Zurhelle) are described by the authors. The main clinical characteristics and histological peculiarities are reviewed. Both cases were disseminated and had typical localisation (pelvic area). The histological examination showed ectopic adipocytes in the dermis. The authors mare a reference to the different hypotheses on the pathogenesi...
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ورودعنوان ژورنال:
- Journal of medical primatology
دوره 36 2 شماره
صفحات -
تاریخ انتشار 2007